The reaction of N-carbobenzoxy-4-piperidylacetic acid (I) with refluxing SOCl2 yields the corresponding acyl chloride (II), which by condensation with indole (III) by means of methylmagnesium iodide (A) in ether gives rise to 3-indolyl-(4-piperidylmethyl)ketone (IV). Finally, this compound is reduced with LiAlH4 in THF.