【药物名称】
化学结构式(Chemical Structure):
参考文献No.485785
标题:Preparation and immunosuppressive activity of 32-(O)-acylated and 32-(O)-thioacylated analogues of ascomycin
作者:Hersperger, R.; Schuler, W.; Zenke, G.
来源:Bioorg Med Chem Lett 1999,9(2),227
合成路线图解说明:

The title compound was obtained by treatment of ascomycin (I) with triphosgene and 4-dimethylaminopyridine at -78 C to produce selectively the 32-hydroxyl mono-acylated product (II), which was subsequently condensed with phenylhydrazine yielding the target phenylcarbazate.

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