J-109404-药物合成数据库

【药物名称】J-109404

化学结构式(Chemical Structure):

参考文献No.	534878
标题:	Synthesis and biological activities of topoisomerase I inhibitors, 6-N-amino analogues of NB-506
作者:	Ohkubo, M.; Kojiri, K.; Kondo, H.; Tanaka, S.; Kawamoto, H.; Nishimura, T.; Nishimura, I.; Yoshinari, T.; Arakawa, H.; Suda, H.; Morishima, H.; Nishimura, S.
来源:	Bioorg Med Chem Lett 1999,9(9),1219

合成路线图解说明: The compound was prepared from the previously reported cyclic anhydride (I), upon condensation with 2-hydrazino-1,3-propanediol (II) in DMF at 80 C.