-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	545150
标题:	Unique analogues of anandamide: Arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas
作者:	Ng, E.W.; Aung, M.M.; Abood, M.E.; Martin, B.R.; Razdan, R.K.
来源:	J Med Chem 1999,421975

合成路线图解说明: Curtius rearrangement of arachidonic acid (I) in the presence of diphenyl phosphoryl azide in hot benzene gave isocyanate (II), which was coupled with methylamine to yield the title urea.

合成路线图解说明: Curtius rearrangement of arachidonic acid (I) in the presence of diphenyl phosphoryl azide in hot benzene gave isocyanate (II), which was coupled with 2-fluoroethylamine (III) to yield the title urea.

合成路线图解说明: Curtius rearrangement of arachidonic acid (I) in the presence of diphenyl phosphoryl azide in hot benzene gave isocyanate (II), which was coupled with ethanolamine (III) to yield the title urea.