ACPA-药物合成数据库

【药物名称】ACPA

化学结构式(Chemical Structure):

参考文献No.	539998
标题:	Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1)
作者:	Hillard, C.J.; Manna, S.; Greenberg, M.J.; Dicamelli, R.; Ross, R.A.; Stevenson, L.A.; Murphy, V.; Pertwee, R.G.; Campbell, W.B.
来源:	J Pharmacol Exp Ther 1999,289(3),1427

合成路线图解说明: Arachidonic acid (I) was converted to the mixed anhydride (II) upon treatment with isobutyl chloroformate and triethylamine. Subsequent condensation of (II) with 2-chloroethylamine (III) provided the target amide.

合成路线图解说明: Arachidonic acid (I) was converted to the mixed anhydride (II) upon treatment with isobutyl chloroformate and triethylamine. Subsequent condensation of (II) with cyclopropylamine (III) provided the target amide.