【药物名称】Methylnaltrexone bromide, MRZ-2663BR
化学结构式(Chemical Structure):
参考文献No.
41822
标题:
Quaternary derivs. of noroxymorphone which relieve intestinal immobility
作者:
Goldberg, L.I.; Stockhaus, K.; Merz, H. (Boehringer Ingelheim GmbH)
来源:
US 4176186
合成路线图解说明:
By quaternization of N-(cyclopropylmethyl)noroxymorphone (I) with methyl bromide in acetone/DMF.
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