【药物名称】CTDP-31677
化学结构式(Chemical Structure):
参考文献No.565867
标题:Discovery of a novel dopamine transporter inhibitor, 4-hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling, structure-activity relationshi
作者:Wang, S.; Sakamuri, S.; Enyedy, I.J.; Kozikowski, A.P.; Deschaux, O.; Bandyopadhyay, B.C.; Tella, S.R.; Zaman, W.A.; Johnson, K.M.
来源:J Med Chem 2000,43(3),351
合成路线图解说明:

The title compound was synthesized by acid-catalyzed condensation of 3',4'-dichloroacetophenone (I) with paraformaldehyde and methylamine.

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