【药物名称】SB-227122
化学结构式(Chemical Structure):
参考文献No.29199
标题:Heterocycle-condensed morphinoid derivs.
作者:Dondio, G.; Ronzoni, S. (SmithKline Beecham plc)
来源:EP 0770081; JP 1998502657; US 5981540; WO 9602545
合成路线图解说明:

The title compound was prepared by condensation of morphinan ketone (I) with N,N-diisopropyl-2-phenylhydrazono-3-oxobutyramide (II) in the presence of zinc dust and NaOAc in hot AcOH.

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