4-Iodopropofol-药物合成数据库

【药物名称】4-Iodopropofol

化学结构式(Chemical Structure):

参考文献No.	45906
标题:	Use derivatives of 2,4-bisubstituted phenols as 5-lipoxigenase inhibitors
作者:	Bonal, J.; et al. (Bobel246 SL)
来源:	WO 9521610

合成路线图解说明: The title compound was obtained by iodination of 2,6-diisopropylphenol (propofol) (I) employing either potassium iodide and hydrogen peroxide or iodonium chloride in HOAc.

参考文献No.	572990
标题:	Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors
作者:	Trapani, G.; Latrofa, A.; Franco, M.; Altomare, C.; Sanna, E.; Usala, M.; Biggio, G.; Liso, G.
来源:	J Med Chem 1998,41(11),1846

合成路线图解说明: The title compound was obtained by iodination of 2,6-diisopropylphenol (propofol) (I) employing either potassium iodide and hydrogen peroxide or iodonium chloride in HOAc.