【药物名称】AWD-33-159
化学结构式(Chemical Structure):
参考文献No.42235
标题:New 4-amino-1-aryl-pyridine-2-ones with anticonvulsive action and method for producing same
作者:Bartsch, R.; Rostock, A.; Lankau, H.-J.; Unverferth, K.; Arnold, T.; Granik, V.; Grizik, S. (AWD.pharma GmbH & Co. KG)
来源:DE 19835918; EP 1102748; JP 2002522420; WO 0007988
合成路线图解说明:

The title N-phenylpyrimidinone was prepared from the previously reported pyrimidine cyano ester (I) by alkaline hydrolysis with 10% NaOH followed by heating at 180 C in 75% H2SO4..

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