MID, IV-2, PX-12-药物合成数据库

【药物名称】MID, IV-2, PX-12

化学结构式(Chemical Structure):

参考文献No.	573019
标题:	Parallel syntheses of disulfide inhibitors of the thioredoxin redox system as potential antitumor agents
作者:	Ulhaq, S.; Kunkel, M.; Watson, S.; Fletcher, S.; Kirkpatrick, D.L.; Powis, G.
来源:	Anti-Cancer Drug Des 1999,14(5),421

合成路线图解说明: The reaction of S-(2-imiazolylsulfanyl)isothiourea (I) with 1-methylpropylthiol (II) by means of NaHCO3 in methanol/water gives the target disulfide.