【药物名称】
化学结构式(Chemical Structure):
参考文献No.585844
标题:Synthesis of tetrakis(multifluoro-4-pyridyl)porphin derivatives as acetylcholinesterase inhibitors
作者:Lee, B.S.; Moon, S.C.; Shin, J.-H.; Jeong, B.H.; Kim, H.-S.; Yu, B.S.; Lee, J.-S.; Namgoong, S.K.
来源:Bioorg Med Chem Lett 2000,10(13),1435
合成路线图解说明:

Lithiation of 3-fluoropyridine (I) followed by formylation with methyl formate afforded aldehyde (II). Porphyrin (IV) was then prepared by condensation of aldehyde (II) with pyrrole (III) in refluxing propionic acid. Methylation of (IV) using methyl p-toluenesulfonate then gave the title pyridinium tosylate salt.

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