【药物名称】
化学结构式(Chemical Structure):
参考文献No.590755
标题:Synthesis and antinociceptive activity of pyrrolidinylnaphthalenes
作者:Collina, S.; Azzolina, O.; Vercesi, D.; Sbacchi, M.; Sheideler, M.A.; Barbieri, A.; Lanza, E.; Ghislandi, V.
来源:Bioorg Med Chem 2000,8(8),1925
合成路线图解说明:

The target (rac)-(cis)-compound is prepared by reaction of the pyrrolidone (II) with the lithiation product obtained by treating the 2-bromo naphthalene (I) in ether with t-BuLi in pentane and by successive treatment with HCl.

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