KTC-5-药物合成数据库

【药物名称】KTC-5

化学结构式(Chemical Structure):

参考文献No.	607950
标题:	Synthesis of 4-alkoxy-2-phenylquinoline derivatives as potent antiplatelet agents
作者:	Ko, T.-C.; Hour, M.J.; Lien, J.C.; Teng, C.M.; Lee, K.H.; Kuo, S.C.; Huang, L.J.
来源:	Bioorg Med Chem Lett 2001,11(3),279

合成路线图解说明: The alkylation of 5-ethyl-2-phenylquinolone (I) with methyl iodide and NaH in THF produces the target methoxyquinoline, along with its N-methylated isomer (II) in a ratio of 1:5.4