PR-9, ME-10092-药物合成数据库

【药物名称】PR-9, ME-10092

化学结构式(Chemical Structure):

参考文献No.	48575
标题:	Guanidine derivs. and their use in the production of a medicament for blocking xanthine oxidase/dehydrogenase
作者:	Skottner, A.; Lundstedt, T.; Seifert, E.; Veveris, M.; Piskunova, I.; Rozhkov, E.; Wikberg, J.; Pett, C.P.; Kalvins, I.; Andrianov, V.; Semenikhina, V.; Dambrova, M. (Melacure Therapeutics)
来源:	WO 0125192

合成路线图解说明: The title compound is prepared by condensation of 2-chloro-3,4-dimethoxybenzaldehyde (I) with aminoguanidine bicarbonate (II) in the presence of HOAc in refluxing MeOH.