【药物名称】NE-10790
化学结构式(Chemical Structure):
参考文献No.26419
标题:Phosphonocarboxylate cpds. for treating abnormal calcium and phosphate metabolism
作者:Bayless, A.V.; Dansereau, S.M.; Ebetino, F.H. (The Procter & Gamble Co.)
来源:EP 0788362; EP 0849272; US 5391743; US 5824661; WO 9324131
合成路线图解说明:

Treatment of ethyl 3-(3-pyridyl)-2-oxopropionate (I) with dimethyl phosphite (II) provides derivative (III), which is finally converted into the desired compound by hydrolysis with HCl.

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