Ibuproxam-药物合成数据库

【药物名称】Ibuproxam

化学结构式(Chemical Structure):

参考文献No.	803945
标题:	Ibuproxam
作者:	Casta馿r, J.; Arrigoni, Martelli, E.
来源:	Drugs Fut 1977,2(12),808

合成路线图解说明: By esterification of 2-(p-isobutylphenyl)propionic acid (I) with ethanol and H2SO4 at reflux temperature yielding the corresponding ethyl ester (II), which is the treated with hydroxylamine in refluxing methanol

参考文献No.	900179
标题:
作者:	Orzalesi, G.; Selleri, R. (Manetti&Roberts)
来源:	DE 2400531; FR 2213062

合成路线图解说明: By esterification of 2-(p-isobutylphenyl)propionic acid (I) with ethanol and H2SO4 at reflux temperature yielding the corresponding ethyl ester (II), which is the treated with hydroxylamine in refluxing methanol