【药物名称】Metralindole
化学结构式(Chemical Structure):
参考文献No.803962
标题:Metralindole
作者:Serradell, M.N.; Casta馿r, J.
来源:Drugs Fut 1984,9(3),195
合成路线图解说明:

By cyclization of 1-oxo-6-methoxy-9-(beta-dimethylaminoethyl)-1,2,3,4-tetrahydro-beta-carboline (I) by means of refluxing phosphorous oxychloride, followed by a treatment with aqueous ammonia. (1,2)

参考文献No.803963
标题:Synthesis and pharmaological activity of pyrazino-beta-carboniles
作者:Glushkov, R.G.; Filenko, N.I.; Mashkovskii, M.D.; Andreeva, N.I.; Sozinov, V.N.
来源:Khim Pharm Zh 1981,5(Suppl. 3),58
合成路线图解说明:

By cyclization of 1-oxo-6-methoxy-9-(beta-dimethylaminoethyl)-1,2,3,4-tetrahydro-beta-carboline (I) by means of refluxing phosphorous oxychloride, followed by a treatment with aqueous ammonia. (1,2)

参考文献No.900194
标题:
作者:Glushkov, R.G.; Mashkovskii, M.D.; Andreeva, N.I.; Liberman, S.S.; Gerchikov, L.N.; Volskova, V.A.; Zaitseva, A.V.; Maggidson, O.Yu. (Ordzhonikadze All-Union Sci. Res, Chem. Pharm. Inst.)
来源:CH 601299; DE 2357320; FR 2213283; GB 1409935; JP 7583398; US 4088647
合成路线图解说明:

By cyclization of 1-oxo-6-methoxy-9-(beta-dimethylaminoethyl)-1,2,3,4-tetrahydro-beta-carboline (I) by means of refluxing phosphorous oxychloride, followed by a treatment with aqueous ammonia. (1,2)

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