Piclonidine, LR-99853-药物合成数据库

【药物名称】Piclonidine, LR-99853

化学结构式(Chemical Structure):

参考文献No.	900304
标题:
作者:	Manghisi, E.; Cascio, G.; Fregnan, G.B.; Ferni, G.
来源:	BE 880502; DE 2949971; FR 2444036; GB 2041355; JP 80160774; NL 7908853; US 4262006; ZA 7906513

合成路线图解说明: By condensation of 2-(2,6-dichlorophenylimino)imidazolidine (I) with 2-chlorotetrahydropyran (II) by means of NaH in methylene chloride.

参考文献No.	950051
标题:	Piclonidine
作者:	Blancafort, P.; Serradell, M.N.; Casta馿r, J.; Hillier, K.
来源:	Drugs Fut 1982,7(8),582

合成路线图解说明: By condensation of 2-(2,6-dichlorophenylimino)imidazolidine (I) with 2-chlorotetrahydropyran (II) by means of NaH in methylene chloride.