【药物名称】Sulmazole, AR-L-115-BS
化学结构式(Chemical Structure):
参考文献No.803993
标题:Sulmazole
作者:Unterhalt, B.
来源:Drugs Fut 1981,6(7),421
合成路线图解说明:

2,3-Pyridiamine (I) is cyclized with 2-methoxy-4-methylmercaptobenzoic acid (II) in the presence of POCl3 to give (III), which is oxidized to AR-L-115-BS by hydrogen peroxide. (1,2)

参考文献No.803994
标题:Radio-Synthese von (14C)-[(2-Methoxy-4-methylsulfinyl)phenyl]-1H-imidazo[4,5-b]pyridin (AR-L 115 BS)
作者:Zipp, H.; et al.
来源:Arzneim-Forsch Drug Res 1981,31(5),200
合成路线图解说明:

2,3-Pyridiamine (I) is cyclized with 2-methoxy-4-methylmercaptobenzoic acid (II) in the presence of POCl3 to give (III), which is oxidized to AR-L-115-BS by hydrogen peroxide. (1,2)

参考文献No.900223
标题:
作者:Kutter, E.; et al. (Dr. Karl Thomae GmbH)
来源:AU 332873; DE 2305339; FR 2215968; GB 1445824; JP 74102693; NL 7401254; US 3985891; ZA 7400695
合成路线图解说明:

2,3-Pyridiamine (I) is cyclized with 2-methoxy-4-methylmercaptobenzoic acid (II) in the presence of POCl3 to give (III), which is oxidized to AR-L-115-BS by hydrogen peroxide. (1,2)

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