12459, Compound 12459-药物合成数据库

【药物名称】12459, Compound 12459

化学结构式(Chemical Structure):

参考文献No.	49584
标题:	Arylamine derivs. and their use as anti-telomerase agent
作者:	Mailliet, P.; Riou, J.-F.; Laoui, A.; Mergny, J.-L.; Lavelle, F.; Petitgenet, O. (Aventis Pharma SA)
来源:	FR 2801588; WO 0140218

合成路线图解说明: By reaction of beta-alanine (I) with the phosphorous acid and PCl3 in chlorobenzene at 100 C.

合成路线图解说明: The condensation of 4,6-dichloro-1,3,5-triazin-2-amine (I) with 6-amino-1-methylquinolinium chloride (II) in refluxing ethanol/water gives the target bis quinolinium chloride.