RPR-201764-药物合成数据库

【药物名称】RPR-201764

化学结构式(Chemical Structure):

参考文献No.	40170
标题:	Condensed heterocyclic system derivs., preparation, pharmaceutical compsns. containing them
作者:	Jimonet, P.; Dereu, N.; Le Brun, A.; Baudoin, B.; Clerc, F.; El-Ahmad, Y.; Hardy, J.-C. (Aventis Pharma SA)
来源:	EP 1054882; FR 2774987; WO 9941248

合成路线图解说明: The target compound has been obtained by reductocondensation of 1-(4-cyanobenzyl)-1H-imidazole-5-carbaldehyde (I) with N2-(4-amino-3,4-dihydro-2H-1-benzopyran-8-ylcarbonyl)-4-chlorophenylalaninamide (II) by means of NaBH3CN and HOAc in acetonitrile.