Tel-01-药物合成数据库

【药物名称】Tel-01

化学结构式(Chemical Structure):

参考文献No.	46123
标题:	Inhibition of human telomerase by a G-quadruplex-interaction cpd.
作者:	Salazar, M.; Kerwin, S.M.; Hurley, L.H.; Fedoroff, O.Y. (University of Texas System)
来源:	US 6156763; WO 9940087

合成路线图解说明: The title bis-imide was synthesized by condensation of 3,4,9,10-perylenetetracarboxylic acid dianhydride (I) with N-(3-aminopropyl)morpholine (II) in hot n-butanol.

参考文献No.	630337
标题:	G-quadruplex DNA binding selectivity of perylenetetracarboxylic acid diimides is PH dependent and mediated by ligand aggregation
作者:	Kerwin, S.M.; et al.
来源:	222nd ACS Natl Meet (Aug 26 2001, Chicago) 2001,Abst MEDI 142

合成路线图解说明: The title bis-imide was synthesized by condensation of 3,4,9,10-perylenetetracarboxylic acid dianhydride (I) with N-(3-aminopropyl)morpholine (II) in hot n-butanol.