【药物名称】
化学结构式(Chemical Structure):
参考文献No.631300
标题:Nicotinamide N-oxides as CXCR2 antagonists
作者:Cutshall, N.S.; Ursino, R.; Kucera, K.A.; Latham, J.; Ihle, N.C.
来源:Bioorg Med Chem Lett 2001,11(14),1951
合成路线图解说明:

6-Chloronicotinic acid (I) was converted to the corresponding N-oxide (II) using trifluoroperacetic acid. Acid (II) was subsequently condensed with 4-fluoroaniline (III) using EEDQ as the coupling reagent to provide the target amide.

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