【药物名称】Fexinidazole, Hoe-239
化学结构式(Chemical Structure):
参考文献No.803982
标题:Chemotherapeutically active nitro compounds. 4,5-Nitroimidazoles. Part III
作者:Winkelman, E.; Raether, W.
来源:Arzneim-Forsch Drug Res 1978,28(5),739
合成路线图解说明:

By condensation of 4-(methylmercapto)phenol (II) with 1-mehtyl-2-chloromethyl-5-nitroimidazole (I) by means of K2CO3 in DMF. (1,2)

参考文献No.803983
标题:Fexinidazole
作者:Blancafort, P.; Serradell, M.N.; Casta馿r, J.
来源:Drugs Fut 1980,5(3),125
合成路线图解说明:

By condensation of 4-(methylmercapto)phenol (II) with 1-mehtyl-2-chloromethyl-5-nitroimidazole (I) by means of K2CO3 in DMF. (1,2)

参考文献No.900213
标题:
作者:Winkelmann, E.; Raether, W. (Hoechst AG)
来源:DE 2531303
合成路线图解说明:

By condensation of 4-(methylmercapto)phenol (II) with 1-mehtyl-2-chloromethyl-5-nitroimidazole (I) by means of K2CO3 in DMF. (1,2)

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