Butikacin, UK-18892-药物合成数据库

【药物名称】Butikacin, UK-18892

化学结构式(Chemical Structure):

参考文献No.	900359
标题:
作者:	Kawaguchi, H.; Naito,T.
来源:	AU 316750; CA 966831; DE 2234315; FR 2145649; GB 1401221; US 3781268; ZA 7204736

合成路线图解说明: 1-N-[(S)-4-Amino-2-hydroxybutyryl]kanamycin A 揃B-K8?(I) is treated with trifluoroacetic acid, and the resulting product is reduced with diborane in THF at 50 C.

参考文献No.	950110
标题:	Butikacin
作者:	Casta馿r, J.; Roberts, P.J.
来源:	Drugs Fut 1979,4(3),178

合成路线图解说明: 1-N-[(S)-4-Amino-2-hydroxybutyryl]kanamycin A 揃B-K8?(I) is treated with trifluoroacetic acid, and the resulting product is reduced with diborane in THF at 50 C.