Amidantel, Bay-d-8815(hydrochloride)-药物合成数据库

【药物名称】Amidantel, Bay-d-8815(hydrochloride)

化学结构式(Chemical Structure):

参考文献No.	950112
标题:	Amidantel, a potent anthelmintic from a new chemical class
作者:
来源:	Arzneim-Forsch 1979,29(1),31

合成路线图解说明: 4-[[(1-Dimethylamino)ethylidene]amino]nitrobenzene (I) is reduced with Raney-Ni to the amine (II), which is condensed with methoxyacetylchloride (III) to give amidantel in 90% yield.

参考文献No.	950113
标题:	Amidantel
作者:	Unterhalt, B.
来源:	Drugs Fut 1979,4(5),315

合成路线图解说明: 4-[[(1-Dimethylamino)ethylidene]amino]nitrobenzene (I) is reduced with Raney-Ni to the amine (II), which is condensed with methoxyacetylchloride (III) to give amidantel in 90% yield.