【药物名称】Pentrinitrol, W-2197
化学结构式(Chemical Structure):
参考文献No.950116
标题:A new synthesis of pentaerythritol trinate
作者:Camp, A.T.; et al.
来源:J Am Chem Soc 1955,77751-752
合成路线图解说明:

It can be prepared in two different ways: 1) By careful nitration of pentaerythritol (I) with 80% nitric acid followed by separation of the tetranitrate (II) (1). 2) By denitration of pentaerythritol tetranitate (II) with N2H4 in refluxing dioxane - ethanol (2).

参考文献No.950117
标题:Organic nitrates. I. Preparation and properties of pentaerythritol nitrates
作者:Simecek, J.
来源:Collection Czech Chem Commun 1962, 27, 362-371 1962,27362-371
合成路线图解说明:

It can be prepared in two different ways: 1) By careful nitration of pentaerythritol (I) with 80% nitric acid followed by separation of the tetranitrate (II) (1). 2) By denitration of pentaerythritol tetranitate (II) with N2H4 in refluxing dioxane - ethanol (2).

参考文献No.950118
标题:Pentinitrol
作者:Blancafort, P.; Serradell, M.N.; Casta馿r, J.; Hillier, K.
来源:Drugs Fut 1979,4(5),351
合成路线图解说明:

It can be prepared in two different ways: 1) By careful nitration of pentaerythritol (I) with 80% nitric acid followed by separation of the tetranitrate (II) (1). 2) By denitration of pentaerythritol tetranitate (II) with N2H4 in refluxing dioxane - ethanol (2).

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