【药物名称】Timofibrate
化学结构式(Chemical Structure):
参考文献No.900427
标题:
作者:
来源:FR 2315271; IT 24693 A/75; JP 773060
合成路线图解说明:

By reacting 2-(p-chlorophenoxy)-2-methylpropanoyl chloride (I) with thiazolidin-4-carboxylic acid (II) in water, in presence of NaOH. It combines in the same molecule, through amidation, a hepatotropic agent, thiazolidine carboxylic acid, with a classic hypolipemiant, clofibric acid.

参考文献No.950185
标题:Timofribate
作者:Neuman, M.
来源:Drugs Fut 1978,3(11),844
合成路线图解说明:

By reacting 2-(p-chlorophenoxy)-2-methylpropanoyl chloride (I) with thiazolidin-4-carboxylic acid (II) in water, in presence of NaOH. It combines in the same molecule, through amidation, a hepatotropic agent, thiazolidine carboxylic acid, with a classic hypolipemiant, clofibric acid.

Drug Information Express,Drug R&D,Chemical Database,Patent Search.
Copyright © 2006-2024 Drug Future. All rights reserved.Contact Us