The target disubstituted piperazine was generated by the ring opening of dimethyl (tetrahydro-3,3-diphenyl-2-furylidene)ammonium bromide (I), equivalent to the open-chain bromobutyramide, with N-(2-methoxyphenyl)piperazine (II) in hot DMF. Subsequent treatment with HCl in CHCl3-Et2O provided the corresponding hydrochloride salt.