【药物名称】
化学结构式(Chemical Structure):
参考文献No.639704
标题:Functionalized amino acid anticonvulsants: Synthesis and pharmacological evaluation of conformationally restricted analogues
作者:Le Tiran, A.; Stables, J.P.; Kohn, H.
来源:Bioorg Med Chem 2001,9(10),2693
合成路线图解说明:

Condensation of alanine methyl ester (I) with benzyl isothiocyanate (II) in the presence of Et3N produced the thiohydantoin (III). This was further acetylated by means of acetic anhydride and DMAP to yield the title compound.

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