-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	647835
标题:	Carbonic anhydrase inhibitors: Anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties
作者:	Masereel, B. ; Rolin, S.; Abbate, F.; Scozzafava, A.; Supuran, C.T.
来源:	J Med Chem 2002,45(2),312

合成路线图解说明: The title compound is prepared by acylation of 5-amino-1,3,4-thiadiazole-2-sulfonamide (I) with valproyl chloride (II) in acetonitrile in the presence of triethylamine.