BIA-3-335-药物合成数据库

【药物名称】BIA-3-335

化学结构式(Chemical Structure):

参考文献No.	52913
标题:	Novel substd. nitrocatechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compsns. containing them
作者:	Learmonth, D.A.; Soares Da Silva, P.M.V.A. (Portela & Ca., SA)
来源:	EP 1167342; WO 0198251

合成路线图解说明: The title compound is prepared by condensation between 2-chloro-1-(3,4-dihydroxy-5-nitrophenyl)ethanone (I) and 1-(3-trifluoromethylphenyl)piperazine (II) in DMF, followed by conversion to the corresponding dihydrochloride salt.