【药物名称】BMS-411886
化学结构式(Chemical Structure):
参考文献No.56256
标题:Water soluble thiazolyl peptide derivs.
作者:Bronson, J.J.; Lam, K.S.; Ueda, Y.; Wichtowski, J.A.; Sorenson, M.E.; Li, W.; Kim, O.K.; Zhang, Y.; Naidu, B.N.; Connolly, T.P. (Bristol-Myers Squibb Co.)
来源:WO 0214354
合成路线图解说明:

The title compound is prepared using nocathiacin I (I) as the starting material. Michael addition of 2-(methylamino)ethanol (II) to the conjugated amide function of (I) in aqueous solution gives rise to the target diaminopropionamide derivative.

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