CT-32228-药物合成数据库

【药物名称】CT-32228

化学结构式(Chemical Structure):

参考文献No.	62132
标题:	6-Phenyl-N-phenyl-(1,3,5)-triazine-2,4-diamine derivs. and related cpds. with lysophosphatidic acid acyltransferase beta (LPAAT-beta) inhibitory activity for use in the treatment of cancer
作者:	Klein, J.P.; Gong, B.; Kumar, A.M.; Bhatt, R.; Tulinsky, J.; Hong, F.; Jenkins, S.A. (Cell Therapeutics, Inc.)
来源:	US 2003153570; WO 0337346

合成路线图解说明: The cyclization of 1-(4-bromophenyl)biguanide (I) with 5-chloro-2-methyl benzoic acid methyl ester (II) by means of NaOEt in refluxing ethanol gives the target triazine derivative.