【药物名称】DL-262
化学结构式(Chemical Structure):
参考文献No.804029
标题:DL - 262
作者:Casta馿r, J.; Hillier, K.
来源:Drugs Fut 1979,4(3),196
合成路线图解说明:

The reaction of aziridine (I) with hydrazine gives aminoethylhydrazine (II) (1), which is then cyclized with ethyl 2,3-diphenylpropionimidate hydrochloride (III) in ethanol. (1,2)

参考文献No.804030
标题:Vitrase approved by FDA as spreading agent; phase III results in vitreous hemorrhage also presented
作者:Trepanier, D.L.; et al.
来源:J Med Chem 1969,12(2),257
合成路线图解说明:

The reaction of aziridine (I) with hydrazine gives aminoethylhydrazine (II) (1), which is then cyclized with ethyl 2,3-diphenylpropionimidate hydrochloride (III) in ethanol. (1,2)

参考文献No.900250
标题:
作者:Trepanier, D.L. (Dow Chem. Co.)
来源:US 3471486
合成路线图解说明:

The reaction of aziridine (I) with hydrazine gives aminoethylhydrazine (II) (1), which is then cyclized with ethyl 2,3-diphenylpropionimidate hydrochloride (III) in ethanol. (1,2)

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