-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	710407
标题:	Stereoselective synthesis of beta-lactams with polyaromatic imines: Entry to new and novel anticancer agents
作者:	Banik, I.; Becker, F.F.; Banik, B.K.
来源:	J Med Chem 2003,46(1),12

合成路线图解说明: The title trans beta-lactam is obtained by condensation of imine (I) with acetyloxyacetyl chloride (II) in the presence of Et3N in cold CH2Cl2 under Staudinger reaction conditions. (1,2)

参考文献No.	718480
标题:	Unprecedented stereoselectivity in the Staudinger reaction with polycyclic aromatic imines
作者:	Banik, N.K.; Becker, F.F.
来源:	Tetrahedron Lett 2000,41(34),6551

合成路线图解说明: The title trans beta-lactam is obtained by condensation of imine (I) with acetyloxyacetyl chloride (II) in the presence of Et3N in cold CH2Cl2 under Staudinger reaction conditions. (1,2)