【药物名称】
化学结构式(Chemical Structure):
参考文献No.602516
标题:Synthesis, antioxidant and anti-inflammatory activity of novel substituted ethylenediamines and ethanolamines. A preliminary quantitative structure-activity relationship study
作者:Andreadou, I.; Rekka, E.A.; Demopoulos, V.J.; Bijloo, G.J.; Kourounakis, P.N.
来源:Arzneim-Forsch Drug Res 1997,47(5),643
合成路线图解说明:

Addition of benzylmagnesium bromide to 4-chlorobutyronitrile (II) gives rise to the chloro ketone adduct (III). Subsequent chloride displacement with ethylenediamine (IV) furnishes the target diamino ketone.

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