-药物合成数据库

【药物名称】

化学结构式(Chemical Structure):

参考文献No.	726115
标题:	Synthesis and analgesic activity of a series of new azaalkane bis-guanidinium and bis(2-aminoimidazolinium) compounds
作者:	Dardonville, C.; Rozas, I.; Goya, P.; Gir髇, R.; Goicoechea, C.; Mart韓, M.I.
来源:	Bioorg Med Chem 2003,11(7),1283

合成路线图解说明: Triamine (I) is condensed with 2-(methylsulfanyl)-4,5-dihydroimidazole hydroiodide (II) to produce the target bis-imidazoline compound. After purification as the picrate salt, treatment with Amberlyte IRA400 (Cl- form) exchange resin generates the corresponding trihydrochloride salt.