【药物名称】
化学结构式(Chemical Structure):
参考文献No.727131
标题:Antiplatelet properties of novel N-substituted-phenyl-1,2,3-triazole-4-acylhydrazone derivatives
作者:Cunha, A.C..; Figueiredo, J.M.; Tributino, J.L.M.; Miranda, A.L.P.; Castro, H.C.; Zingali, R.B.; Fraga, C.A.M.; de Souza, M.C.B.V.; Ferreira, V.F.; Barreiro, E.J.
来源:Bioorg Med Chem 2003,11(9),2051
合成路线图解说明:

The triazolecarboxaldehyde (I) is oxidized by means of MnO2 in the presence of NaCN in MeOH to produce the methyl ester (II). Subsequent reaction of ester (II) with hydrazine hydrate leads to hydrazide (III). This is then condensed with 4-bromobenzaldehyde (IV) to furnish the target acylhydrazone derivative.

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