【药物名称】FKK
化学结构式(Chemical Structure):
参考文献No.64767
标题:FKK
作者:Serradell, M.N.; Casta馿r, J.; Chu, S.S.
来源:Drugs Fut 1984,9(4),264
合成路线图解说明:

By cyclization of 5-methyl-3-phenylindazole (I) with 1,3-dibromopropane (II) by means of NaH in DMF or triethylbenzylammonium chloride NaOH in toluene - water.

参考文献No.604463
标题:Pharmacologic potency and selectivity of a new bronchodilator agent, 2,3-dihydro-7-methyl-9-phenyl-1H-pyrazolo[1,2-a]indazolium bromide (FKK) on canine tracheal preparations 'in vivo' and 'in vitro'
作者:Shiraki, Y.; Sakai, K.
来源:Arch Intl Pharmacodyn Ther 1983,262(1),150-163
合成路线图解说明:

By cyclization of 5-methyl-3-phenylindazole (I) with 1,3-dibromopropane (II) by means of NaH in DMF or triethylbenzylammonium chloride NaOH in toluene - water.

参考文献No.701165
标题:Pyrazoloindazole derivatives and bronchodilating composition
作者:Fujimura, Y.; et al.
来源:EP 0023633; JP 56015287; US 4409234
合成路线图解说明:

By cyclization of 5-methyl-3-phenylindazole (I) with 1,3-dibromopropane (II) by means of NaH in DMF or triethylbenzylammonium chloride NaOH in toluene - water.

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