【药物名称】Foscarnet sodium, EHB-776, PFA, A-29622, Triapten, Virudin, Foscavir
化学结构式(Chemical Structure):
参考文献No.66392
标题:Foscarnet sodium
作者:Casta馿r, J.; Blancafort, P.; Hopkins, S.J.; Serradell, M.N.
来源:Drugs Fut 1980,5(7),345
合成路线图解说明:

The reduction of triethyl phosphite (I) with ethyl chloroformate (II) gives phosphonoformic acid triethyl ester (III), which is hydrolyzed with refluxing aqueous NaOH. Other alkyl esters can be used instead.

参考文献No.700913
标题:Carboxyphosphonates
作者:McIntosh, C.L.
来源:US 4018854
合成路线图解说明:

The reduction of triethyl phosphite (I) with ethyl chloroformate (II) gives phosphonoformic acid triethyl ester (III), which is hydrolyzed with refluxing aqueous NaOH. Other alkyl esters can be used instead.

参考文献No.700914
标题:Carboxyphosphonate brush control agents
作者:McIntosh, C.L.
来源:US 4042650
合成路线图解说明:

The reduction of triethyl phosphite (I) with ethyl chloroformate (II) gives phosphonoformic acid triethyl ester (III), which is hydrolyzed with refluxing aqueous NaOH. Other alkyl esters can be used instead.

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