Falipamil, AQ-A-39-药物合成数据库

【药物名称】Falipamil, AQ-A-39

化学结构式(Chemical Structure):

参考文献No.	66386
标题:	AQ-A-39
作者:	Casta馿r, J.; Koch, H.
来源:	Drugs Fut 1981,6(7),402

合成路线图解说明: The condensation of 4,5-dimethoxyphthalic anhydride (I) with 3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propylamine (II) in refluxing acetic acid gives 5,6-dimethoxy-2-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propylphthalamide (III), which is reduced with Zn in refluxing acetic acid.

参考文献No.	701372
标题:
作者:	Eberlein, W.; et al.
来源:	US 4038407

合成路线图解说明: The condensation of 4,5-dimethoxyphthalic anhydride (I) with 3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propylamine (II) in refluxing acetic acid gives 5,6-dimethoxy-2-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propylphthalamide (III), which is reduced with Zn in refluxing acetic acid.