【药物名称】Nafimidone hydrochloride, RS-81943
化学结构式(Chemical Structure):
参考文献No.47229
标题:1-(Naphthylethyl)imidazole derivs., their preparation, and pharmaceutical compsns. containing them
作者:Walker, K.A.M. (Syntex (USA), Inc.)
来源:EP 0001926
合成路线图解说明:

By reaction of 2-naphthyl bromomethyl ketone (I) with imidazole (II) in DMF, followed by a treatment with HCl in ether.

参考文献No.47230
标题:Imidazole derivs., their preparation and their use in pharmaceutical compsns.
作者:Walker, K.A.M. (Syntex (USA), Inc.)
来源:EP 0013786
合成路线图解说明:

By reaction of 2-naphthyl bromomethyl ketone (I) with imidazole (II) in DMF, followed by a treatment with HCl in ether.

参考文献No.70113
标题:Nafimidone hydrochloride
作者:Serradell, M.N.; Blancafort, P.; Casta馿r, J.
来源:Drugs Fut 1983,8(8),689
合成路线图解说明:

By reaction of 2-naphthyl bromomethyl ketone (I) with imidazole (II) in DMF, followed by a treatment with HCl in ether.

参考文献No.607590
标题:1-(Naphthylalyl)-1H-imidazole derivatives, a new class of anticonvulsant agents
作者:Walker, K.A.M.; Wallach, M.B.; Hirschfeld, D.R.
来源:J Med Chem 1981,24(1),67
合成路线图解说明:

By reaction of 2-naphthyl bromomethyl ketone (I) with imidazole (II) in DMF, followed by a treatment with HCl in ether.

参考文献No.701260
标题:
作者:Walker, K.A.M.
来源:GB 1540023
合成路线图解说明:

By reaction of 2-naphthyl bromomethyl ketone (I) with imidazole (II) in DMF, followed by a treatment with HCl in ether.

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