The reaction of 2-bromo-4-fluorophenylacetic acid (I) with 4-isopropytthiophenol (II) by means of Cu and K2CO3 in DMF at 100 C gives 4-fluoro-2-(4-isopropylphenylthio)phenylacetic acid (III), which is cyclized by treatment with polyphosphoric acid at 1 500 yielding 3-fluoro-8-isopropyldibenzo[b,f]-thiepin-10(11H) one (IV). The reduction of (IV) with NaBH4 in ethanol affords 3-fluoro-10-hydroxy-8-isopropyl-10,11-dihydrodibenzo[b,f]thiepin (V), which is treated with SOCl2 refluxing benzene to give 10-chloro-3-fluoro-8-isopropyl-10,11-dihydro-dibenzo[b,f]thiepin (VI). Finally, this compound is condensed with 1-(2-hydroxyethyl)piperazine (VII) in refluxing CHCl3.