【药物名称】Riodipine, PP-1466, Foridone, Phoridone
化学结构式(Chemical Structure):
参考文献No.46037
标题:2,6-Dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)1,4-dihydropyridine
作者:Dubur, G.Y.
来源:DE 2900537; FR 2414501; GB 2013186; JP 79122280; US 4219653
合成路线图解说明:

By cyclization of 2-(difluoromethoxy)benzaldehyde (I) with methyl acetoacetate (II) and refluxing aqueous concentrated ammonia.

参考文献No.75322
标题:Riodipine
作者:Serradell, M.N.; Casta馿r, J.
来源:Drugs Fut 1985,10(11),922
合成路线图解说明:

By cyclization of 2-(difluoromethoxy)benzaldehyde (I) with methyl acetoacetate (II) and refluxing aqueous concentrated ammonia.

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