Locicortolone dicibate, Locicortone, Ru-24643-药物合成数据库

【药物名称】Locicortolone dicibate, Locicortone, Ru-24643

化学结构式(Chemical Structure):

参考文献No.	46624
标题:	Novel 16alpha-methylpregnane
作者:	Teutsch, J.G.; Deraedt, R. (Aventis Pharma SA)
来源:	DE 3028255; FR 2462443; GB 2054600; JP 56022798; US 4353899

合成路线图解说明: By esterification of 9alpha,11alpha-dichloro-16alpha-methyl-21-hydroxy-pregna-1,4-dien-3,20-dione (I) with dicycloheylmethyl chloroformate (II) by means of pyridine in dioxane.

参考文献No.	67222
标题:	RU-24643
作者:	Serradell, M.N.; Casta馿r, J.
来源:	Drugs Fut 1985,10(6),470

合成路线图解说明: By esterification of 9alpha,11alpha-dichloro-16alpha-methyl-21-hydroxy-pregna-1,4-dien-3,20-dione (I) with dicycloheylmethyl chloroformate (II) by means of pyridine in dioxane.