Pilsicainide hydrochloride, DU-6552, SUN-1165, Sunrythm-药物合成数据库

【药物名称】Pilsicainide hydrochloride, DU-6552, SUN-1165, Sunrythm

化学结构式(Chemical Structure):

参考文献No.	46028
标题:	8-(Substituted-N-phenylcarboxamidomethyl)pyrrolizidines and use thereof as antiarrhythmics
作者:	Miyano, S.; Sumoto, K.; Morita, M.; Sato, F. (Suntory Ltd.)
来源:	EP 0089061; JP 58159793; US 4564624

合成路线图解说明: By condensation of 2,6-dimethylaniline (I) with 8-pyrrolizineacetlc acid (II) by means of NaH in refluxing dioxane.

参考文献No.	67114
标题:	SUN-1165
作者:	Thorpe, P.J.; Serradell, M.N.; Casta馿r, J.
来源:	Drugs Fut 1985,10(6),483

合成路线图解说明: By condensation of 2,6-dimethylaniline (I) with 8-pyrrolizineacetlc acid (II) by means of NaH in refluxing dioxane.