Fenretinide, NSC-374551, McN-R-1967, HPR, 4-HPR-药物合成数据库

【药物名称】Fenretinide, NSC-374551, McN-R-1967, HPR, 4-HPR

化学结构式(Chemical Structure):

参考文献No.	49519
标题:	4-Hydroxyphenylretinamide
作者:	Hillier, K.; Blancafort, P.; Serradell, M.N.; Casta馿r, J.
来源:	Drugs Fut 1980,5(3),132

合成路线图解说明: The reaction of retinoic acid (I) with PCl3 in dry benzene gives the corresponding retinoyl chloride (II), which is then condensed with 4-aminophenol (III) in DMF - ether.

参考文献No.	700890
标题:	Esters of retinoic acid
作者:	Gander, R.J.; Gurney, J.A.
来源:	BE 0847942; CA 1062700; GB 1543824; NL 7612201; US 4108880

合成路线图解说明: The reaction of retinoic acid (I) with PCl3 in dry benzene gives the corresponding retinoyl chloride (II), which is then condensed with 4-aminophenol (III) in DMF - ether.