4-Nitro-2-methylindazole (I) is reduced with H2 over Pd/C in ethyl acetate to give 4-amino-2-methylindazole (II). The condensation of a mixture of 4-amino-2-methylindazole (III) dissolved in tetrahydrofuran and 2-chloroimidazoline (A) in tetrahydrofuran solution in room temperature gives Sgd-101-75.